The various applications of the YubiKey 5 Series and YubiKey 5 FIPS Series are separate, and reset individually. Each application, along with a link to the related reset instructions, is listed below.
| Application | Reset Instructions |
| OTP | Resetting the OTP Application on the YubiKey |
| FIDO U2F / FIDO 2 | Resetting the FIDO-U2F / FIDO2 Application on Your Yubikey |
| PIV (Smart Card) | Resetting the Smart Card (PIV) Application on Your YubiKey |
| OATH | Resetting the OATH Application on the YubiKey |
| OpenPGP | Resetting the OpenPGP Application on Your YubiKey |
| YubiHSM Auth* | Resetting the YubiHSM Auth Application on the YubiKey |
*The YubiHSM Auth application is only available in YubiKey firmware 5.4 or higher. Use YubiKey Manager to check your YubiKey's firmware version.